Key result
During postural change, young women had a greater reduction in stroke volume index compared with young men (-22.9 vs -14.4 ml/m2), but compensatory mechanisms preserved mean arterial pressure.
Why the study?
How do systemic hemodynamics and cerebral blood flow respond to postural change across different age and sex groups?
Population
37 individuals including 7 young women, 11 young men, 10 older women, and 9 older men
Comparison
Supine-to-sit-to-stand test (postural change) vs Comparisons between sexes and age groups
Design
Cross-sectional
Authors
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Hormonal factors may influence orthostatic tolerance in young women; leaves open sex- and age-specific cerebrovascular responses to postural change.
Observational (n=37)
How do systemic hemodynamics and cerebral blood flow respond to postural change across different age and sex groups?
Absolute Event Rate: -22.9% vs -14.4%
Despite greater reductions in stroke volume during orthostatic stress in women, compensatory increases in heart rate and vascular resistance preserve mean arterial pressure and cerebral blood flow velocity.
Edgell et al. (2012) reported an observational. Female sex vs. Male sex was evaluated on Change in stroke volume index from supine to standing. During postural change, young women had a greater reduction in stroke volume index compared with young men (-22.9 vs -14.4 ml/m2), but compensatory mechanisms preserved mean arterial pressure.
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