Key result
Obesity is an independent risk factor for developing heart failure, yet mild to moderate obesity is associated with a better prognosis in patients with established heart failure, a phenomenon known as the obesity paradox.
Why the study?
Understanding the obesity paradox is important in heart failure given the high prevalence of obesity in these patients.
This review summarizes the complex relationship between obesity and heart failure, including the obesity paradox where overweight/mildly obese patients may have better short-to-moderate term prognosis.
Obesity paradox in HF warrants cautious weight management; leaves open optimal strategies pending prospective trials.
Obesity is an independent predictor of cardiovascular diseases (CVD), including heart failure (HF). Nevertheless, numerous studies have shown that patients with CVD who are overweight and slightly obese have a better short-term and moderate prognosis than thinner patients with CVD. This phenomenon has been called the obesity paradox. Understanding the obesity paradox is important in patients with HF, given the high prevalence of obesity in patients with HF. The article presents an overview of clinical studies devoted to the study of obesity as a risk factor for HF, the pathogenesis of HF in obesity, and highlights the issues of the obesity paradox and the treatment of obesity in this category of patients.
No takes yet. Share an insight, caveat, or question.
Сафиуллина et al. (2022) conducted a review in Heart failure and obesity. Obesity vs. Normal weight was evaluated. Obesity is an independent risk factor for developing heart failure, yet mild to moderate obesity is associated with a better prognosis in patients with established heart failure, a phenomenon known as the obesity paradox.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: