Key result
Aging in rats is associated with outward hypertrophic remodeling and vascular stiffening of mesenteric arteries, though distensibility appears preserved due to geometric adaptation.
Why the study?
Does aging alter the mechanical properties and stiffness of small mesenteric arteries in rats?
Does aging alter the mechanical properties and stiffness of small mesenteric arteries in rats?
Aging in rats induces outward hypertrophic remodeling in small mesenteric arteries, which preserves distensibility despite the stiffening of wall components.
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Aging stiffens rat small mesenteric arteries; leaves open relevance to human resistance vessel mechanics and hypertension.
Laurant et al. (2004) studied Aging. Aging vs. Younger rats (2, 4, 15 months) was evaluated on Mechanical properties of mesenteric small arteries. Aging in rats is associated with outward hypertrophic remodeling and vascular stiffening of mesenteric arteries, though distensibility appears preserved due to geometric adaptation.
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