Key result
2-dimensional transesophageal echocardiography measurement of PFO size significantly correlated with invasive balloon sizing (r2=0.8; P<0.0001), though it underestimated mean diameter (5.2 vs 8.3 mm).
Why the study?
Does 2D TEE measurement or contrast TEE accurately correlate with invasive balloon sizing for quantifying PFO size in patients with cryptogenic stroke?
Population
100 patients with cryptogenic stroke undergoing catheter closure of patent foramen ovale (PFO)
Comparison
2-dimensional transesophageal echocardiography… vs Invasive balloon sizing
Design
Cross-sectional
Authors
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Clinicians should interpret 2D TEE PFO measurements with caution; leaves open need for outcome-validated sizing.
Observational (n=100)
Does 2D TEE measurement or contrast TEE accurately correlate with invasive balloon sizing for quantifying PFO size in patients with cryptogenic stroke?
Effect estimate: r2=0.8
Absolute Event Rate: 5.2% vs 8.3%
p-value: p=<0.0001
2D TEE measurement of PFO size correlates strongly with invasive balloon sizing and is more accurate than traditional contrast techniques, particularly when contrast is administered via a cubital vein.
Schuchlenz et al. (2002) conducted an observational in Cryptogenic stroke and patent foramen ovale (n=100). 2-dimensional transesophageal echocardiography (2D TEE) vs. Invasive balloon sizing was evaluated on PFO size measurement (r2=0.8, p=<0.0001). 2-dimensional transesophageal echocardiography measurement of PFO size significantly correlated with invasive balloon sizing (r2=0.8; P<0.0001), though it underestimated mean diameter (5.2 vs 8.3 mm).
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