What question did this study set out to answer?

This research aims to characterize the NSILA-s receptor in liver plasma membranes and compare its properties to those of the insulin receptor.

The NSILA-s receptor in liver plasma membranes. Characterization and comparison with the insulin receptor

View Full Paper

Ask AI

Bookmark

This research aims to characterize the NSILA-s receptor in liver plasma membranes and compare its properties to those of the insulin receptor.
Characterization of NSILA-s and insulin receptor binding in liver plasma membranes using 125I-labeled peptides.
Comparison of binding kinetics and pH optima for both receptors.
Analysis of biological activity of various NSILA-s preparations against their receptor binding.
Maximal NSILA-s binding occurs at 20 degrees Celsius; insulin binding peaks at 1-4 degrees.
NSILA-s receptor shows a broader pH optimum (6.0 to 8.0) compared to the sharper optimum (7.5 to 8.0) of the insulin receptor.
There are approximately 50 times more insulin receptors than NSILA-s receptors in liver cells, with NSILA-s receptors having a higher affinity.

No takes yet. Share an insight, caveat, or question.

Comparison of NSILA-s and insulin receptors in liver membranes reveals distinct binding properties and specificity.

Megyesi et al. (1975) studied this question.

View Full Paper

Ask AI

Bookmark