Key result
Radiofrequency ablation of idiopathic ventricular arrhythmias from the right ventricular outflow tract resulted in a reduction of symptoms in 91.2% of patients at 10-year follow-up (p < 0.001).
Why the study?
Does radiofrequency ablation improve long-term symptoms and quality of life in patients with idiopathic ventricular arrhythmias from the right ventricular outflow tract?
Cohort (n=34)
Does radiofrequency ablation improve long-term symptoms and quality of life in patients with idiopathic ventricular arrhythmias from the right ventricular outflow tract?
p-value: p=< 0.001
Radiofrequency ablation for idiopathic RVOT ventricular arrhythmias provides sustained 10-year improvements in symptoms, general health perception, and employment status.
BACKGROUND: The aim of this study was to examine the effect of radiofrequency ablation (RFA) of ventricular arrhythmias from right ventricular outflow tract (RVOT) during long-term follow-up. METHODS: A follow-up analysis was conducted using an in-house questionnaire, as well as a qualitative assessment of the patients' medical records. The study population of 34 patients had a previous diagnosis of idiopathic VT or frequent PVCs from the RVOT, and received RFA treatment between 2002 and 2005. RESULTS: The main symptoms prior to RFA were palpitations (82.4%) and dizziness (76.5%). A reduction in symptoms following RFA was reported by 91.2% of patients (p < 0.001). Furthermore, there was a reduced use of antiarrhythmic medication after RFA (p < 0.001). General health perception classified on a scale of 1 (poor) to 4 (excellent), improved from median class 1 to 3 (p < 0.001) during long-term follow-up. The fitness to work increased from median class 3 to class 5 (1 = incapacitated, 5 = full time employment, p = 0.038), while the rate of patients in full time employment increased from 26.5% to 55.9% after RFA (p = 0.02). CONCLUSIONS: A reduction of symptoms and use of antiarrhythmic medication, as well as an improvement in the general health perception and fitness to work after RFA of idiopathic ventricular arrhythmias can be demonstrated at ten-year follow-up.
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Rørvik et al. (2016) conducted a cohort in Idiopathic ventricular arrhythmias from right ventricular outflow tract (n=34). Radiofrequency ablation (RFA) vs. Pre-ablation baseline was evaluated on Reduction in symptoms (p=< 0.001). Radiofrequency ablation of idiopathic ventricular arrhythmias from the right ventricular outflow tract resulted in a reduction of symptoms in 91.2% of patients at 10-year follow-up (p < 0.001).
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