Key result
Cancer stem cells within renal clear cell carcinoma express components of the renin-angiotensin system, including PRR, ACE2, and AT2R.
Why the study?
This study investigated the expression of renin-angiotensin system components by cancer stem cells recently demonstrated in renal clear cell carcinoma.
Observational (n=15)
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Suggests RAS activity in RCCC CSCs; leaves open targeted therapy exploration pending validation.
Siljee et al. (2021) conducted an observational in Renal clear cell carcinoma (n=15). Renin-angiotensin system components was evaluated on Expression of renin-angiotensin system components by cancer stem cells. Cancer stem cells within renal clear cell carcinoma express components of the renin-angiotensin system, including PRR, ACE2, and AT2R.
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