January 1, 2005Neuroepidemiology
Influence of Gender on Baseline Features and Clinical Outcomes among 17,370 Patients with Confirmed Ischaemic Stroke in the International Stroke Trial
Key result
Female gender was an independent predictor of death or dependency at 6 months following acute ischemic stroke, with women experiencing higher case fatality and more severe strokes than men.
Why the study?
Does female gender independently predict worse clinical outcomes in patients with acute ischemic stroke?
Population
17,370 patients with confirmed ischemic stroke from the International Stroke Trial
Comparison
Female gender vs Male gender
Design
Cohort
Follow-up
6 months
Authors
Discussion
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Member takes
Implication
Women had distinct baselines and outcomes in IST; leaves open whether sex-specific strategies improve care.
Study Design
Type
Cohort (n=17,370)
Multicenter
Yes
Structured PICO
Does female gender independently predict worse clinical outcomes in patients with acute ischemic stroke?
P
Population
17,370 patients with acute ischemic stroke confirmed by CT or autopsy from the International Stroke Trial, followed for 6 months to evaluate the influence of gender on clinical outcomes.
E
Exposure
Female gender
C
Comparator
Male gender
O
Outcome
Death or dependency at 6 monthshard clinical
Female patients with acute ischemic stroke have more severe baseline characteristics and worse clinical outcomes, including higher rates of death or dependency at 6 months, compared to males.
Cite This Study
Niewada et al. (2005) conducted a cohort in Acute ischemic stroke (n=17,370). Female gender vs. Male gender was evaluated on Death or dependency at 6 months. Female gender was an independent predictor of death or dependency at 6 months following acute ischemic stroke, with women experiencing higher case fatality and more severe strokes than men.