Enzymatic Activity in the M Band
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Implication
Randomized trial assesses enzymatic activity in diaphragmatic and cardiac muscle, suggesting roles of specific enzymes.
Key Points
- The research aims to identify the sites and nature of enzymatic hydrolysis in muscle tissues affected by lead ions.
- Histochemistry and electron microscopy were utilized to study enzymatic activities.
- Experiments were conducted on diaphragmatic and cardiac muscle tissues.
- Control experiments tested the effects of various esterase inhibitors.
- The electron opaque product PbS was found on swelling thick filaments at the M band in muscle tissues.
- Additional enzymatic activity was identified in mitochondria and round sarcoplasmic bodies.
- Cholinesterase is suggested as the M band enzyme, with distinct enzymes present in mitochondria and sarcoplasmic bodies.
Cite This Study
Barrnett et al. (1959) studied this question.