Key result
Coexpression of KCNQ2 and KCNQ3 resulted in a 15-fold synergistic increase in peak current amplitude compared to individual expression (14.2 vs 0.98).
Answers are grounded in this paper and cite their sources.
The functional interaction between KCNQ2 and KCNQ3 provides a mechanistic framework for understanding how mutations in these potassium channels cause benign familial neonatal convulsions.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Yang et al. (1998) studied Benign familial neonatal convulsions (BFNC). Coexpression of KCNQ2 and KCNQ3 vs. Expression of KCNQ2 or KCNQ3 individually was evaluated on Potassium current amplitude. Coexpression of KCNQ2 and KCNQ3 resulted in a 15-fold synergistic increase in peak current amplitude compared to individual expression (14.2 vs 0.98).
Synapse has enriched 10 related papers. Consider them for comparative context: