Key result
Following the arterial switch operation, neonates exhibited impaired left ventricular performance and decreased isovolumic relaxation time compared with normal data.
Why the study?
Does the arterial switch operation alter postoperative left ventricular mechanics in neonates with transposition of the great arteries?
Cohort (n=9)
Does the arterial switch operation alter postoperative left ventricular mechanics in neonates with transposition of the great arteries?
Answers are grounded in this paper and cite their sources.
Following the arterial switch operation in neonates, left ventricular performance is impaired primarily due to a preload deficit and impaired compliance, rather than decreased contractility.
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Bryant et al. (1998) conducted a cohort in Transposition of the great arteries (n=9). Arterial switch operation (ASO) vs. Normal age- and body surface area-adjusted population was evaluated on Left ventricular performance (stress-shortening relation) and isovolumic relaxation time (IVRT) (p=<.001). Following the arterial switch operation, neonates exhibited impaired left ventricular performance and decreased isovolumic relaxation time compared with normal data.
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