Why the study?
Does the arterial switch operation alter postoperative left ventricular mechanics in neonates with transposition of the great arteries?
Population
9 neonates with transposition of the great arteries undergoing the arterial switch operation within the…
Comparison
Arterial switch operation (ASO) vs Normal age- and body surface area-adjusted…
Design
Cohort
Follow-up
48 hours
Key result
Following the arterial switch operation, neonates exhibited impaired left ventricular performance and decreased isovolumic relaxation time compared with normal data (p < 0.001).
Authors
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Following the arterial switch operation in neonates, left ventricular performance is impaired primarily due to a preload deficit and impaired compliance, rather than decreased contractility.
Cohort (n=9)
Does the arterial switch operation alter postoperative left ventricular mechanics in neonates with transposition of the great arteries?
p-value: p=<.001
Following the arterial switch operation in neonates, left ventricular performance is impaired primarily due to a preload deficit and impaired compliance, rather than decreased contractility.
Bryant et al. (1998) conducted a cohort in Transposition of the great arteries (n=9). Arterial switch operation (ASO) vs. Normal age- and body surface area-adjusted population was evaluated on Left ventricular performance (stress-shortening relation) and isovolumic relaxation time (IVRT) (p=<.001). Following the arterial switch operation, neonates exhibited impaired left ventricular performance and decreased isovolumic relaxation time compared with normal data (p < 0.001).
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