Key result
Higher total serum carotenoid levels were significantly associated with a lower prevalence of nonalcoholic fatty liver disease, with an odds ratio of 0.41 for the highest versus lowest quartile.
Why the study?
Are higher serum carotenoid levels associated with a lower prevalence of NAFLD in Chinese adults?
Population
2935 Chinese adults aged 40-75 years
Comparison
Higher serum carotenoid levels vs Lowest quartile of serum carotenoid levels
Design
Cross-sectional
Authors
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Serum carotenoids inversely associated with NAFLD prevalence; hypothesis-generating and requires prospective studies before any clinical recommendations.
Cross-Sectional (n=2,935)
Are higher serum carotenoid levels associated with a lower prevalence of NAFLD in Chinese adults?
Odds Ratio: 0.41 (95% CI 0.32–0.53)
Absolute Event Rate: 36.8% vs 65.6%
p-value: p=<0.001
Higher serum carotenoid levels are associated with a lower prevalence and severity of NAFLD in middle-aged and elderly Chinese adults.
Cao et al. (2015) conducted a cross-sectional in Nonalcoholic fatty liver disease (NAFLD) (n=2,935). Total serum carotenoids vs. Lowest quartile of total serum carotenoids was evaluated on Prevalence of nonalcoholic fatty liver disease (NAFLD) (OR 0.41, 95% CI 0.32, 0.53, p=<0.001). Higher total serum carotenoid levels were significantly associated with a lower prevalence of nonalcoholic fatty liver disease, with an odds ratio of 0.41 for the highest versus lowest quartile.
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