Key result
Free-breathing 3D MRCA with HOPE detected coronary stenosis with a sensitivity of 89% (CI 65%-99%) for the LAD and 76% (CI 50%-93%) for the RCA, but only 50% (CI 21%-79%) for the LCx.
Why the study?
Does free-breathing 3D MRCA with HOPE accurately detect proximal coronary artery stenosis compared to cardiac catheterization in patients undergoing catheterization?
Population
46 patients undergoing cardiac catheterization, of which 23 had coronary artery disease with 47 significant…
Comparison
Free-breathing, prospective navigator-gated… vs Cardiac catheterization (reference standard)
Design
Cross-sectional
Authors
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Supports feasibility of navigator-gated 3D MRCA for proximal coronary visualization; leaves open diagnostic accuracy versus catheterization in larger studies.
Cross-Sectional (n=46)
Does free-breathing 3D MRCA with HOPE accurately detect proximal coronary artery stenosis compared to cardiac catheterization in patients undergoing catheterization?
Free-breathing 3D MRCA with HOPE shows moderate to high sensitivity for LAD and RCA stenosis but requires improvements in image quality and LCx visualization to serve as a viable alternative to cardiac catheterization.
Bunce et al. (2001) conducted a cross-sectional in Proximal coronary artery stenosis (n=46). Free-breathing 3D magnetic resonance coronary angiography (MRCA) with hybrid ordered phase-encoding (HOPE) vs. Cardiac catheterization was evaluated on Detection of proximal coronary artery stenosis. Free-breathing 3D MRCA with HOPE detected coronary stenosis with a sensitivity of 89% (CI 65%-99%) for the LAD and 76% (CI 50%-93%) for the RCA, but only 50% (CI 21%-79%) for the LCx.
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