Key result
A causal, parametric beat-to-beat model faithfully tracked expected changes in autonomic balance resulting from changing posture (P<0.01) and sympathetic blockade (P<0.05).
Why the study?
Accurate quantitative models of the arterial baroreflex are needed to provide physiological insight and enable real-time tracking of autonomic nervous system activity in clinical settings.
p-value: p=<0.01
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Causal baroreflex model may enable real-time ANS tracking; leaves open prospective clinical validation.
Birjiniuk et al. (2018) studied Healthy (n=14). Pharmacological blockade and postural changes was evaluated on Changes in autonomic balance (p=<0.01). A causal, parametric beat-to-beat model faithfully tracked expected changes in autonomic balance resulting from changing posture (P<0.01) and sympathetic blockade (P<0.05).
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