Key result
Among patients undergoing rotational atherectomy, presentation with acute myocardial infarction was associated with a significantly higher risk of 1-year cardiovascular major adverse cardiac events compared to non-AMI presentation (adjusted OR 1.79).
Why the study?
Rotational atherectomy is used for calcified lesion preparation in PCI, but its use in acute myocardial infarction is challenged by limited clinical data.
Does rotational atherectomy have acceptable procedural and clinical outcomes in patients presenting with acute myocardial infarction compared to those without AMI?
Cohort (n=411)
No
Does rotational atherectomy have acceptable procedural and clinical outcomes in patients presenting with acute myocardial infarction compared to those without AMI?
Odds Ratio: 1.79 (95% CI 1.02–3.15)
Absolute Event Rate: 30.8% vs 19.1%
p-value: p=0.042
Rotational atherectomy is feasible in patients with AMI with high procedural success and acceptable periprocedural complications, though long-term clinical outcomes remain worse compared to non-AMI patients.
No takes yet. Share an insight, caveat, or question.
RA feasible in AMI with comparable complications; leaves open whether it improves hard outcomes versus non-RA strategies in calcified lesions.
Chen et al. (2022) conducted a cohort in Coronary Artery Disease requiring Rotational Atherectomy (n=411). Acute myocardial infarction vs. Non-acute myocardial infarction was evaluated on 1-year cardiovascular major adverse cardiac events (CV MACE) (OR 1.79, 95% CI 1.02-3.15, p=0.042). Among patients undergoing rotational atherectomy, presentation with acute myocardial infarction was associated with a significantly higher risk of 1-year cardiovascular major adverse cardiac events compared to non-AMI presentation (adjusted OR 1.79).
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