Key result
Among patients undergoing rotational atherectomy, acute coronary syndrome presentation was associated with a higher 24-month risk of MACE compared to stable disease (39.9% vs 22.4%; HR 1.39, P=0.003).
Why the study?
Does rotational atherectomy in patients with acute coronary syndrome have similar feasibility, safety, and long-term outcomes compared to patients with stable coronary artery disease?
Observational (n=541)
No
Does rotational atherectomy in patients with acute coronary syndrome have similar feasibility, safety, and long-term outcomes compared to patients with stable coronary artery disease?
Hazard Ratio: 1.39 (95% CI 1.12–1.73)
Absolute Event Rate: 39.9% vs 22.4%
p-value: p=0.003
Rotational atherectomy is feasible and safe in ACS patients with similar procedural success to SCAD patients, though long-term MACE remains significantly higher in the ACS population.
No takes yet. Share an insight, caveat, or question.
RA feasible in selected ACS; leaves open comparative safety/efficacy versus SCAD and precludes practice change.
Allali et al. (2018) conducted an observational in Acute coronary syndrome and stable coronary artery disease (n=541). Acute coronary syndrome presentation vs. Stable coronary artery disease was evaluated on MACE within 24 months (HR 1.39, 95% CI 1.12-1.73, p=0.003). Among patients undergoing rotational atherectomy, acute coronary syndrome presentation was associated with a higher 24-month risk of MACE compared to stable disease (39.9% vs 22.4%; HR 1.39, P=0.003).
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