Key result
Moderate or severe pulmonary hypertension independently predicted 3-year MACE in AMI patients after PCI, with event rates of 39.3% and 68.4% respectively, compared to 18.9% in those with normal RVSP.
Why the study?
The role of pulmonary hypertension in long-term clinical outcomes was unclear in patients with acute myocardial infarction, and the significance of elevated RVSP on echocardiography is often underestimated.
Does elevated right ventricular systolic pressure (pulmonary hypertension) predict major adverse cardiac events in patients with acute myocardial infarction after successful percutaneous coronary intervention?
Population
2,526 AMI patients after successful PCI with pre-discharge TTE from the Korean AMI registry
Comparison
Normal RVSP vs mild vs moderate vs severe PH
Design
Registry-based cohort study
Follow-up
3-year
Authors
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Elevated RVSP warrants closer monitoring in AMI post-PCI; confirms independent MACE risk beyond traditional factors.
Cohort (n=2,526)
Yes
Does elevated right ventricular systolic pressure (pulmonary hypertension) predict major adverse cardiac events in patients with acute myocardial infarction after successful percutaneous coronary intervention?
Elevated right ventricular systolic pressure (moderate or severe pulmonary hypertension) on routine pre-discharge echocardiography is an independent predictor of long-term major adverse cardiac events in patients with acute myocardial infarction following successful PCI.
Cho et al. (2022) conducted a cohort in Acute myocardial infarction (n=2,526). Pulmonary hypertension (elevated RVSP) vs. Normal RVSP (< 35 mmHg) was evaluated on Major adverse cardiac events (MACE). Moderate or severe pulmonary hypertension independently predicted 3-year MACE in AMI patients after PCI, with event rates of 39.3% and 68.4% respectively, compared to 18.9% in those with normal RVSP.
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