Stiffness of Carotid Artery Wall Material and Blood Pressure in Humans
Key result
Increased carotid wall stiffness with age causes a disproportionate increase in systolic and pulse pressure, highlighting the need for therapies targeting large artery walls.
Population
Middle-aged hypertensive patients and elderly subjects
Design
Review
Authors
Discussion
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Member takes
Implication
Antihypertensive therapy may improve carotid properties; reinforces BP optimization for stroke prevention in hypertensives.
Structured PICO
P
Population
Middle-aged hypertensive patients and elderly subjects
New therapeutic approaches targeting large artery wall stiffness or wave reflections are needed to treat hypertension in elderly patients and prevent cardiovascular events.
Cite This Study
Safar et al. (2000) conducted a review in Hypertension. Carotid wall stiffness was evaluated. Increased carotid wall stiffness with age causes a disproportionate increase in systolic and pulse pressure, highlighting the need for therapies targeting large artery walls.