Key result
Increased carotid wall stiffness with age causes a disproportionate increase in systolic and pulse pressure, highlighting the need for therapies targeting large artery walls.
New therapeutic approaches targeting large artery wall stiffness or wave reflections are needed to treat hypertension in elderly patients and prevent cardiovascular events.
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Antihypertensive therapy may improve carotid properties; reinforces BP optimization for stroke prevention in hypertensives.
Safar et al. (2000) conducted a review in Hypertension. Carotid wall stiffness was evaluated. Increased carotid wall stiffness with age causes a disproportionate increase in systolic and pulse pressure, highlighting the need for therapies targeting large artery walls.
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