Hypertension and arterial stiffness: the atherosclerosis risk in communities study*1
Why the study?
Is hypertension associated with increased carotid arterial stiffness in adults free of cardiovascular disease?
Population
10,712 men and women, ages 45 to 64 years, from the Atherosclerosis Risk in Communities Study, free of…
Comparison
Hypertension vs Optimal blood pressure (BP < 120/80 mm Hg)
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Hypertension-linked carotid stiffness may reflect distending pressure; leaves open reversibility with BP control in primary prevention.
Structured PICO
Is hypertension associated with increased carotid arterial stiffness in adults free of cardiovascular disease?
P
Population
10,712 men and women, ages 45 to 64 years, from the Atherosclerosis Risk in Communities Study, free of prevalent cardiovascular disease.
I
Intervention
Hypertension (systolic or diastolic BP ≥140/90 mm Hg or current use of antihypertensive medications)
C
Comparator
Optimal blood pressure (BP < 120/80 mm Hg)
O
Outcome
Common carotid arterial diameter change measured using B-mode ultrasoundsurrogate
Hypertension is associated with increased carotid arterial stiffness, which appears to be driven by distending pressure rather than structural changes.
Cite This Study
Arnett et al. (2000) studied this question.