Key result
A lower aortic root dimension z-score was independently associated with high arterial stiffness in hypertensive patients (OR 0.83; 95% CI 0.79-0.88; P<0.0001).
Population
12,392 hypertensive patients free of prevalent cardiovascular disease and with ejection fraction ≥50%, from…
Design
Cross-sectional
Authors
Loading...
Smaller ARD may flag higher stiffness in hypertension; leaves open whether it refines risk stratification or therapy.
Observational (n=12,392)
Yes
Odds Ratio: 0.83 (95% CI 0.79–0.88)
p-value: p=<0.0001
In hypertensive patients, a smaller aortic root dimension and increased carotid intima-media thickness are independently associated with higher arterial stiffness.
Lønnebakken et al. (2016) conducted an observational in arterial hypertension (n=12,392). Aortic root dimension (ARD) z-score was evaluated on High arterial stiffness (highest population tertile of pulse pressure/stroke index) (OR 0.83, 95% CI 0.79-0.88, p=<0.0001). A lower aortic root dimension z-score was independently associated with high arterial stiffness in hypertensive patients (OR 0.83; 95% CI 0.79-0.88; P<0.0001).