Key result
Hyponatremia after subarachnoid hemorrhage was associated with significantly higher plasma BNP concentrations compared to healthy controls (P<0.05).
Why the study?
Is brain natriuretic peptide (BNP) related to hyponatremia following subarachnoid hemorrhage?
Population
18 patients with subarachnoid hemorrhage (SAH) and healthy controls
Design
Cohort
Follow-up
> 14 days
Authors
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May link BNP to post-SAH hyponatremia; leaves open causal role and therapeutic targets.
Observational (n=18)
Is brain natriuretic peptide (BNP) related to hyponatremia following subarachnoid hemorrhage?
p-value: p=<0.05
Elevated plasma BNP concentrations may contribute to hyponatremia and natriuresis following subarachnoid hemorrhage, potentially driven by increased noradrenaline.
Tomida et al. (1998) conducted an observational in Subarachnoid Hemorrhage (n=18). Hyponatremia vs. Normonatremia and healthy controls was evaluated on Plasma BNP concentrations (p=<0.05). Hyponatremia after subarachnoid hemorrhage was associated with significantly higher plasma BNP concentrations compared to healthy controls (P<0.05).
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