Why the study?
Are BNP plasma concentrations associated with cerebral vasospasm in patients with spontaneous subarachnoid hemorrhage?
Population
19 patients with spontaneous subarachnoid hemorrhage (SAH)
Comparison
Measurement of BNP plasma concentrations at 4… vs Control subjects and SAH patients without severe…
Design
Cohort
Follow-up
10 to 12 days
Authors
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BNP rise was associated with symptomatic CVS in SAH; leaves open any predictive or therapeutic role pending prospective validation.
Are BNP plasma concentrations associated with cerebral vasospasm in patients with spontaneous subarachnoid hemorrhage?
BNP plasma levels increase markedly during the first week in SAH patients with symptomatic cerebral vasospasm, suggesting a potential role in exacerbating blood flow reduction.
Sviri et al. (2000) studied this question.