Key result
Angiotensin II receptors AT1 and AT2 have been cloned and characterized, revealing distinct structural features, functional domains, and complex regulatory mechanisms.
Population
Rodent and mammalian tissues and cell lines used for cloning and expressing Angiotensin II receptors
Design
Review
Authors
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Informs AT1/AT2-targeted research; leaves open clinical translation in hypertension.
This review details the molecular cloning, structural domains, signaling pathways, and transcriptional regulation of the angiotensin II receptor subtypes AT1 and AT2.
Inagami et al. (1994) conducted a review in Angiotensin II receptor function and regulation. Angiotensin II receptors (AT1 and AT2) was evaluated. Angiotensin II receptors AT1 and AT2 have been cloned and characterized, revealing distinct structural features, functional domains, and complex regulatory mechanisms.
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