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This analysis explores the current landscape and trends in the research of sepsis-associated acute kidney injury (SA-AKI) pathophysiology.

July 26, 2026MedicineOpen Access

A bibliometric analysis of the pathophysiology of sepsis-associated acute kidney injury from 2015 to 2024

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Bibliometric analysis shows trends in sepsis-associated acute kidney injury research, indicating crucial developments and future directions.

This analysis explores the current landscape and trends in the research of sepsis-associated acute kidney injury (SA-AKI) pathophysiology.
Conducted bibliometric analysis using publications from the Web of Science Core Collection database from 2015 to 2024.
Utilized tools like CiteSpace, VOSviewer, and the bibliometric package in R for visualization and trend analysis.
Analyzed publication trends, citation data, and the contributions of various institutions and authors.
Publication and citation counts have steadily increased in the past decade, with China leading (690 publications, 71.06%).
The United States had extensive collaboration; seven of the top ten institutions were in China.
Key research mechanisms include inflammation, microcirculation dysfunction, metabolic reprogramming, and frontiers like pyroptosis and ferroptosis.

Qi et al. (2026) studied this question.

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Bibliometric analysis shows trends in sepsis-associated acute kidney injury research, indicating crucial developments and future directions.