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July 26, 2026The American Surgeon

Protective Ileostomy After Low Anterior Resection for Rectal Cancer: Modifying the Clinical Course of Anastomotic Leakage at the Cost of Stoma-Related Morbidity

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Authors

MYMustafa YılmazMBMahsum BarçinCÖCumhur Özcan

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Overview

Retrospective analysis evaluates the effects of protective ileostomy on anastomotic leakage outcomes in rectal cancer patients, suggesting improved management but increased morbidity.

Key Points

  • This study aims to evaluate the effects of protective ileostomy on the clinical outcomes of anastomotic leakage following low anterior resection for rectal cancer.
  • Retrospective review of patients who underwent total mesorectal excision with low anterior resection post-neoadjuvant therapy.
  • Patients were grouped into LAR alone (n = 10) and LAR + protective ileostomy (n = 74).
  • Main outcomes assessed included anastomotic leakage incidence, severity, management, mortality, and protective ileostomy-related morbidity.
  • Anastomotic leakage occurred in 5.9% of patients, showing no significant difference between groups (LAR 10.0% vs LAR + PI 5.4%; P = 0.478).
  • Leak-related mortality was observed in 1 LAR patient, with no cases in the PI group.
  • Length of hospital stay was significantly longer for the PI group (median 10.0 days) compared to LAR alone (7.5 days; P < 0.001).

Cite This Study

Yılmaz et al. (2026) studied this question.

synapsesocial.com/papers/6a65a962d3aea3239cd7948chttps://doi.org/10.1177/00031348261471475
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Balancing benefit and burden: a critical appraisal of prophylactic ileostomy in laparoscopic low anterior resection2026
  2. 2Impact of Surgical Approach, Patient Risk Factors, and Diverting Ileostomy on Anastomotic Leakage and Outcomes After Rectal Cancer Resection: A 5-Year Single-Center Study2025 · 6 citations
  3. 3Prophylactic defunctioning stomas improve clinical outcomes of anastomotic leak following rectal cancer resections: An analysis of the US Rectal Cancer Consortium2024 · 12 citations
  4. 4Comparison analysis of short-term outcomes between degradable stent placement and diverting ileostomy in mid-to-low rectal cancer: a retrospective cohort study2026
  5. 5Chronic Anastomotic Leaks After Low Anterior Resection: Rethinking Evaluation and Management.2026