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Hypoxic stimulation of carotid chemoreceptors causes moderate heart rate slowing, demonstrating that cardiac acceleration during generalized hypoxia does not originate at the carotid bodies.
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Questions carotid chemoreflex origin of hypoxic tachycardia; leaves open alternative mechanisms for targeted investigation.
Changes in heart rate were recorded during the application of hypoxic stimuli limited to the carotid chemoreceptors. 2. The direct reflex change in heart rate initiated by hypoxia at the carotid chemoreceptors was a slowing of moderate degree. 3. It is concluded that the cardiac acceleration of generalized hypoxia does not arise chemoreflexly at the carotid bodies.
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Bernthal et al. (1951) studied this question. Hypoxic stimulation of carotid chemoreceptors causes moderate heart rate slowing, demonstrating that cardiac acceleration during generalized hypoxia does not originate at the carotid bodies.
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