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October 18, 2016EBioMedicineOpen Access

Ectopic Adipose Tissue Storage in the Left and the Right Renal Sinus is Asymmetric and Associated With Serum Kidney Injury Molecule-1 and Fibroblast Growth Factor-21 Levels Increase

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Key result

Renal sinus adipose tissue accumulates asymmetrically, predominantly in the left kidney, and is positively associated with increased serum levels of KIM-1 and FGF-21.

Population

280 asymptomatic participants in a cross-sectional study and 40 in a follow-up study, mean age 38.30±4.10…

Design

Cross-sectional

Authors

GKGita KrieviņaRiga Stradiņš UniversityPTPēteris TretjakovsRiga Stradiņš UniversityISIlze SkujaRiga Stradiņš University

Discussion

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Overview

RS fat volume associates with elevated sKIM-1/FGF-21; leaves open causal role in obesity-related kidney injury.

Study Design

Type

Cross-Sectional (n=320)

Structured PICO

P
Population
320 asymptomatic participants (mean age 38.3 years) evaluated in cross-sectional and follow-up studies for renal sinus adipose tissue volume and its association with sKIM-1 and FGF-21 levels.
O
Outcome
Renal sinus (RS) and abdominal adipose tissue volumes, and their association with serum kidney injury molecule (sKIM)-1 and fibroblast growth factor (FGF)-21 levels.surrogate

Cite This Study

Krieviņa et al. (2016) conducted a cross-sectional in Asymptomatic (n=320). Renal sinus adipose tissue accumulation was evaluated on Association of sKIM-1 and FGF-21 levels with renal sinus adipose tissue volume. Renal sinus adipose tissue accumulates asymmetrically, predominantly in the left kidney, and is positively associated with increased serum levels of KIM-1 and FGF-21.

synapsesocial.com/papers/6a676d3b4340feaedbb2a7dehttps://doi.org/10.1016/j.ebiom.2016.10.020
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Also Consider

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