Key result
In patients with type 2 diabetes, higher renal sinus fat volume was negatively correlated with glomerular filtration rate (r = -0.38) and positively correlated with effective renal vascular resistance (r = 0.45).
Why the study?
Increased renal sinus fat is associated with hypertension and chronic kidney disease, but the underlying mechanisms are incompletely understood.
Is renal sinus fat volume associated with altered renal hemodynamics in patients with type 2 diabetes?
Population
Type 2 diabetes patients
Comparison
Renal sinus fat volume quantified by MRI-scanning
Design
Cross-sectional analysis
Authors
Loading...
RSF may relate to renal hemodynamics in T2D; leaves open causal role in hypertension or CKD.
Cross-Sectional (n=51)
No
Is renal sinus fat volume associated with altered renal hemodynamics in patients with type 2 diabetes?
Effect estimate: r = -0.38
p-value: p=0.006
Higher renal sinus fat volume is associated with increased renal vascular resistance and decreased GFR in patients with type 2 diabetes, suggesting a potential mechanism for hypertension and CKD development.
Spit et al. (2019) conducted a cross-sectional in Type 2 diabetes (n=51). Renal sinus fat (RSF) volume was evaluated on Correlation between renal sinus fat (RSF) and glomerular filtration rate (GFR) (r = -0.38, p=0.006). In patients with type 2 diabetes, higher renal sinus fat volume was negatively correlated with glomerular filtration rate (r = -0.38) and positively correlated with effective renal vascular resistance (r = 0.45).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: