Coronary Artery Calcium Score and Carotid Intima-Media Thickness As Markers of Computed Tomography Angiographic Severity in Coronary Artery Disease: A Cross-Sectional Study

Figure 1. Axial non-contrast cardiac computed tomography demonstrating color-coded calcified plaques in the left anterior descending artery (yellow), left circumflex artery (cyan), and right coronary artery (red) used for Agatston scoring.

Figure 2. Dedicated software (Syngo Calcium Scoring) report displaying per-vessel lesion count, volume, equivalent mass, and total Agatston CACS (447.7 in this representative case). CACS: Coronary Artery Calcium Score. Syngo Calcium Scoring (Siemens Healthcare GmbH, Erlangen, Bavaria, Germany).

Figure 3. CT coronary angiography (curved planar reformation; Syngo.via) of the right coronary artery (RCA). The arrow marks a significant stenotic segment contributing to elevated Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery (SYNTAX) and Gensini scores in this patient. Syngo.via workstation (Siemens Healthcare GmbH, Erlangen, Bavaria, Germany).

Figure 4. B-mode ultrasound of the left proximal common carotid artery demonstrating far-wall CIMT measurement of 0.88 mm. CIMT: Carotid Intima-Media Thickness.

Figure 5. B-mode ultrasound of the right proximal common carotid artery demonstrating far-wall carotid intima media thickness measurement of 0.77 mm.

Figure 6. Scatter plot with a fitted simple linear regression line demonstrating the relationship between Agatston CACS on the x-axis and CT-derived SYNTAX score on the y-axis. Pearson correlation analysis showed a strong positive correlation between the two variables (r = 0.813, p < 0.001). Simple linear regression yielded the equation y = 2.21 + 0.05x with a coefficient of determination R² = 0.660 (n = 75). Each circle represents an individual patient. SYNTAX: Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery; CACS: Coronary Artery Calcium Score.

Figure 7. Scatter plot with a fitted simple linear regression line demonstrating the relationship between Agatston CACS on the x-axis and CT-derived Gensini score on the y-axis. Pearson correlation analysis revealed a strong positive correlation between the two variables (r = 0.851, p < 0.001). Simple linear regression yielded the equation y = −0.41 + 0.07x with a coefficient of determination R² = 0.724 (n = 75). Each circle represents an individual patient. CACS: Coronary Artery Calcium Score.

Figure 8. Scatter plot with a fitted simple linear regression line demonstrating the relationship between CIMT (mm) on the x-axis and CT-derived SYNTAX score on the y-axis. Pearson correlation analysis showed a moderate positive correlation between the two variables (r = 0.583, p < 0.001). Simple linear regression yielded the equation y = −10.02 + 32x with a coefficient of determination R² = 0.340 (n = 75). Each circle represents an individual patient. SYNTAX: Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery; CIMT: Carotid Intima-Media Thickness.

Figure 9. Scatter plot with a fitted simple linear regression line demonstrating the relationship between CIMT (mm) on the x-axis and CT-derived Gensini score on the y-axis. Pearson correlation analysis revealed a moderate-to-strong positive correlation between the two variables (r = 0.694, p < 0.001). Simple linear regression yielded the equation y = −22.14 + 49.91x with a coefficient of determination R² = 0.482 (n = 75). Each circle represents an individual patient. CIMT: Carotid Intima-Media Thickness.