Key result
Bivalirudin use during cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia resulted in a large thrombus forming in the venous reservoir, likely due to blood stasis.
Population
1 patient with heparin-induced thrombocytopenia undergoing heart transplantation
Design
Case_report
Authors
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Urges caution with bivalirudin for CPB in HIT; leaves open optimal monitoring and stasis-prevention strategies.
Case Report (n=1)
Bivalirudin use during cardiopulmonary bypass in patients with heparin-induced thrombocytopenia may be complicated by thrombus formation in the venous reservoir due to blood stasis, and ACT may not accurately reflect anticoagulation status.
Wong et al. (2010) conducted a case report in Heparin-induced thrombocytopenia undergoing heart transplantation (n=1). Bivalirudin was evaluated on Thrombus formation in the venous reservoir. Bivalirudin use during cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia resulted in a large thrombus forming in the venous reservoir, likely due to blood stasis.
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