Key result
Cardiovascular and orthopedic surgeries are associated with potentially severe acute postoperative depletions in plasma/serum concentrations of numerous vitamins, particularly vitamins C, D, and B1.
Why the study?
Major surgical volumes are rising and surgical trauma causes metabolic changes, but the effects of orthopedic and cardiovascular surgery on vitamin concentrations and their underlying mechanisms needed summarizing.
Does cardiovascular and orthopedic surgery affect plasma/serum vitamin concentrations?
Does cardiovascular and orthopedic surgery affect plasma/serum vitamin concentrations?
Major surgeries, including cardiovascular procedures, may cause significant acute depletions in essential vitamins like C, D, and B1, warranting further investigation into their clinical significance.
Postoperative vitamin depletion may warrant monitoring after cardiac or orthopedic surgery; leaves open whether repletion improves outcomes.
Given the rise in worldwide chronic diseases, supplemented by an aging population, the volume of global major surgeries, encompassing cardiac and orthopedic procedures is anticipated to surge significantly. Surgical trauma can be accompanied by numerous postoperative complications and metabolic changes. The present review summarized the results from studies assessing the effects of orthopedic and cardiovascular surgery on vitamin concentrations, in addition to exploring the possible mechanisms associated with changes in concentrations. Studies have revealed a potentially severe depletion in plasma/serum concentrations of numerous vitamins following these surgeries acutely. Vitamins C, D and B1 appear particularly vulnerable to significant depletions, with vitamin C and D depletions consistently transpiring into inadequate and deficient concentrations, respectively. The possible multifactorial mechanisms impacting postoperative vitamin concentrations include changes in hemodilution and vitamin utilization, redistribution, circulatory transport and absorption. For a majority of vitamins, there has been a lack of investigation into the effects of both, cardiac and orthopedic surgery. Additionally, studies were predominantly restricted to short-term postoperative investigations, primarily performed within the first postoperative week of surgery. Overall, results indicated that further examination is necessary to determine the severity and clinical significance of the possible depletions in vitamin concentrations that ensue cardiovascular and orthopedic surgery.
No takes yet. Share an insight, caveat, or question.
Travica et al. (2021) conducted a review in Cardiovascular and orthopedic surgery. Cardiovascular and orthopedic surgery was evaluated on Vitamin concentrations. Cardiovascular and orthopedic surgeries are associated with potentially severe acute postoperative depletions in plasma/serum concentrations of numerous vitamins, particularly vitamins C, D, and B1.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: