Key result
Each 5 ng/mL increase in serum vitamin D was associated with decreased odds of in-hospital mortality and severe morbidity after noncardiac surgery (OR 0.93; 95% CI 0.88-0.97; P=0.003).
Why the study?
Does higher preoperative serum vitamin D concentration reduce the risk of in-hospital mortality, cardiovascular morbidity, and serious infections in patients undergoing noncardiac surgery?
Population
3,509 patients who had noncardiac surgery at the Cleveland Clinic Main Campus and had a preoperative serum…
Comparison
Higher serum vitamin D concentration vs Lower serum vitamin D concentration
Design
Cohort
Follow-up
in-hospital
Authors
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Should not yet alter perioperative vitamin D management; hypothesis-generating for randomized supplementation trials.
Observational (n=3,509)
No
Does higher preoperative serum vitamin D concentration reduce the risk of in-hospital mortality, cardiovascular morbidity, and serious infections in patients undergoing noncardiac surgery?
Effect estimate: OR 0.93 (95% CI 0.88-0.97)
p-value: p=0.003
Higher preoperative serum vitamin D concentrations are associated with a significantly lower risk of in-hospital death, serious infections, and cardiovascular events after noncardiac surgery.
Turan et al. (2014) conducted an observational in Noncardiac surgery (n=3,509). Serum vitamin D concentration vs. Lower vitamin D concentration was evaluated on All-cause in-hospital mortality, in-hospital cardiovascular morbidity, and serious in-hospital infections (OR 0.93, 95% CI 0.88-0.97, p=0.003). Each 5 ng/mL increase in serum vitamin D was associated with decreased odds of in-hospital mortality and severe morbidity after noncardiac surgery (OR 0.93; 95% CI 0.88-0.97; P=0.003).
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