Key result
Oral inoculation of turkey poults with the reovirus ARV-CU98 caused intestinal alterations and significantly lower relative bursa and liver weights (P<=0.05), reproducing some clinical signs of PEMS.
Population
Turkey poults
Comparison
Oral inoculation with 100-nm filtrate of PEMS… vs Oral inoculation with 100-nm filtrate of control…
Design
Preclinical
Follow-up
6 days postinfection
Authors
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ARV-CU98 may contribute to PEMS in poults; leaves open causality and field relevance.
p-value: p=<=0.05
The reovirus ARV-CU98 isolated from PEMS fecal material causes some clinical signs of PEMS in turkey poults, suggesting it may contribute directly or indirectly to the syndrome.
Heggen-Peay et al. (2002) studied Poult enteritis and mortality syndrome (PEMS). ARV-CU98 (reovirus) / 100-nm PEMS fecal filtrate vs. Control fecal filtrate / uninoculated controls was evaluated on Body weight, relative bursa, thymus, and liver weights, and mortality (p=<=0.05). Oral inoculation of turkey poults with the reovirus ARV-CU98 caused intestinal alterations and significantly lower relative bursa and liver weights (P<=0.05), reproducing some clinical signs of PEMS.
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