Key result
Elevated troponin links to higher in-hospital mortality and worse prognosis in acute ischemic stroke.
Why the study?
The exact mechanisms of interaction between the brain and heart remain unclear, meriting particular attention following sudden brain injury such as acute ischemic stroke.
This narrative review highlights that myocardial injury, evidenced by troponin elevation, frequently complicates acute ischemic stroke and signifies a worse prognosis.
May prompt enhanced cardiac surveillance in acute ischemic stroke; extends brain-heart literature but leaves management implications open.
Since antiquity, the interaction of brain and heart has inspired physicians and philosophers. Today, our knowledge has vastly improved, but the exact way of their interaction still holds many secrets to reveal. The interaction between brain and heart merits particular attention in the aftermath of a sudden injury to the brain-like acute ischemic stroke (AIS). This narrative review gives an overview of current knowledge on frequency, prognosis, and potential pathophysiological mechanisms of myocardial injury following AIS.
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Nolte et al. (2021) conducted a review in Acute ischemic stroke. Myocardial injury and elevated cardiac troponin was evaluated. Elevated cardiac troponin is detectable in 30-60% of acute ischemic stroke patients and is associated with worse prognosis, including higher in-hospital mortality.
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