VIEWING ONLY POSTERS1323Evaluation of right ventricular transverse strain and strain rate in patients with acute ST-segment elevation myocardial infarction: a cardiac magnetic resonance feature tracking study1333Cardiac resynchronization in ischemic heart failure patients: a comparison between therapy guided by cardiac magnetic resonance imaging and 2D-speckle tracking echocardiography1338Cardiac magnetic resonance versus bisphosphonate scintigraphy for diagnosis of cardiac amyloidosis1341Strain relaxation index, a novel tagged MRI-derived diastolic function parameter, is impaired in metabolic syndrome1349Global Longitudinal Strain Predicts Chronic Myocardial Infarction in Patients with Normal Ejection Fraction1352Optimal Dose Of Dobutamine During Low-Dose Dobutamine Stress Echocardiography In Correctly Identify Viable Segments On Cardiovascular Magnetic Resonance1368Absolute wall thickening and left ventricular ejection fraction–a unifying theory of myocardial contraction and heart failure?1376Transient St Elevation in Acs Like Myocarditis1379Patients after Fontan with a “total cavopulmonary connection” Fontan modification develop more collateral flow compared to “old-fashioned” Fontan modifications1387A MRI–derived 3D patient specific model for fibrosis quantification in atrial fibrillation1391Scar burden and survival in patients with ischemic cardiomyopathy and poor LV ejection fraction1392Relation of inflammatory markers with myocardial and microvascular injury in patients with reperfused ST- elevation myocardial infarction1406Equivalence of segmented conventional and fast single-shot late gadolinium enhancement (LGE) techniques for1410Cardiac Mri Appearances of Tuberculosis - A Review of Varied Presentations in India1415Atheroma burden, cardiac remodelling and epicardial fat: A comparison between healthy South Asian and European adults using Whole Body Cardiovascular MR1418Symptomatic Ventricular Arrhythmias: Diagnostic Yield of Cardiac Magnetic Resonance1421CMR assessment of aortic stiffness in asymptomatic low risk patients with type 2 diabetes mellitus1436Shock index as a predictor of myocardial damage and clinical outcome in ST-elevation myocardial infarction1451Combined biomarker testing for the prediction of microvascular obstruction after primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction1452A novel oscillometric technique compared with cardiac magnetic resonance for the assessment of aortic pulse wave velocity in ST-segment elevation myocardial infarction1456Aorto-pulmonary collaterals evaluated by CMR is associated to reduced “effective” cardiac index late after Fontan palliation1458Evaluation of pulmonary transit time and Pulmonary Blood Volume with first-pass perfusion CMR imaging in adult with repaired Congenital Heart disease1459Prognostic value of the cardiac magnetic resonance as a predictor of improvement in ventricular function after TakoTsubo syndrome1462Diagnostic performance of ECG detection of left atrial enlargement in patients with arterial hypertension relative to the cardiac magnetic resonance gold-standard: impact of obesity1463Utility of cardiac magnetic resonance imaging for diagnosis of cardiac sarcoidosis and prediction of therapeutic effects in patients with complete heart block and implanted magnetic resonance-conditional pacemaker: A multicenter study1467Cardiac magnetic resonance late gadolinium enhancement in patients with genetic dilated cardiomyopathy14712.Left ventricular hypertrophy in hypertensive patients–comparison of Cardiac Magnetic Resonance and Echocardiographic analysis of morphological and functional LV-parameters1472Is Angiographic Perfusion Score assessed in patients with acute myocardial infarction correlated with Cardiac Magnetic Resonance infarct size and N-terminal pro-brain natriuretic peptide in 6-month follow-up1476Cardiac Magnetic Resonance Patterns of Left Ventricular Diastolic Function In Hypertrophic Cardiomyopathy1477Impact of platelet volume on thrombus burden and tissue reperfusion in patients with STEMI treated with primary angioplasty: MRI study1479Right ventricle systolic function assessment and its prognostic implications in cardiac amyloidosis1484Cardiac MRI - an important tool in the evaluation of multsystemic inflamatory diseases. An Erdheim-Chester Disease case report1485Predictive value of cardiac magnetic resonance for future adverse cardiac events in patients with ST-segment elevation myocardial infarction1486Time-to-treatment but not thrombectomy influence infarct size and microvascular obstruction in patients with acute ST-segment elevation myocardial infarction treated with primary coronary intervention1489Primary PCI versus Early Routine Post Fibrinolysis PCI for ST Elevation Myocardial Infarction1490Evaluation of ventricular function in Fontan patients undergoing feature tracking magnetic resonance strain1491Impacts of atrialized right ventricle and left ventricular displacement

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Acute isolated left ventricular ST-segment elevation myocardial infarction (n=38). Intervention: Acute isolated left ventricular STEMI vs. Controls. Primary outcome: Mean right ventricular free wall transverse strain (p=0.0001).

Tomas Lapinskas; Chiodi Elisabetta; Chrysanthos Grigoratos; Ricardo Ladeiras‐Lopes; GJ. Fent; E. Abdul Rahman; Jonathan Rodrigues; G Gibelli; Naira Mkrtchyan; Maddalena Valinoti; Evangelia Nyktari; Martin Reindl; Kristin Arnhold; Zeeshan Lakhani; Jonathan Weir‐McCall; Claudia Camaioni; Rachel Kan; Sebastian J. Reinstadler; Hans‐Josef Feistritzer; Hans‐Josef Feistritzer; Pierluigi Festa; Loubna Ali; A. Tercero Martínez; Tamás Erdei; Makoto Orii; Alexandra A. de Sousa; Agata Brzozowska-Czarnek; Agata Brzozowska-Czarnek; Pilar Agudo-Quílez; Nazario Carrabba; Luís Almeida-Morais; Ramona Bica; J. Rajewska-Tabor; J. Rajewska-Tabor; Sameh Mohamed Shaheen; Akio Inage; Akio Inage; Albert TEIS; Arthur Cescau; Alberto Cipriani; Maximilian von Roeder; Ahmad A. Mahmoud; Franz Duca; Hoi Lam She; Barbara Burkhardt; Graeme Bainbridge; Max Charalambos; B Igual Munoz; Carla Contaldi; B Igual Munoz; B. Igual Muñoz; O.V. Mochula; H C van den Bosch; M. Frick; Klug Gert; aSara E. Fawal; Jessica Webb; А. С. Максимова; Agnes Mayr; Michiel M. Winter; Menacho Katia; Juan Sztajzel; Theano Papavassiliu; S. Baig; Nerejda Shehu; João Pais; Giulia Vinco; Jessica Webb; Vivian P. Kamphuis; M. Bensaoud; Masieh Abawi; Chiodi Elisabetta; Chiodi Elisabetta; TA. Musa; Chun‐Ho Yun; Caroline Richmond; Antonella Meloni; Antonella Meloni; LE. Dobson; Christopher Schneeweis; JRJ. Foley; S. Matthew; A. Meloni; Michael Y. Henein; Marco Barbanti; Gabriella Vincenti; Bernard P. Paelinck; Dario Leone; A. Meloni; F. Pizzino; Laura Saunders; F. Macaione; Andreas A. Kammerlander; Maciej Haberka; Sajid Aslam; Anne Bethke; Najime Bouhzam; JRJ. Foley; Siri Lagethon Heck; Josephine Kermer

doi:10.1093/ehjci/jew183

May 1, 2016European Heart Journal - Cardiovascular ImagingOpen Access

VIEWING ONLY POSTERS1323Evaluation of right ventricular transverse strain and strain rate in patients with acute ST-segment elevation myocardial infarction: a cardiac magnetic resonance feature tracking study1333Cardiac resynchronization in ischemic heart failure patients: a comparison between therapy guided by cardiac magnetic resonance imaging and 2D-speckle tracking echocardiography1338Cardiac magnetic resonance versus bisphosphonate scintigraphy for diagnosis of cardiac amyloidosis1341Strain relaxation index, a novel tagged MRI-derived diastolic function parameter, is impaired in metabolic syndrome1349Global Longitudinal Strain Predicts Chronic Myocardial Infarction in Patients with Normal Ejection Fraction1352Optimal Dose Of Dobutamine During Low-Dose Dobutamine Stress Echocardiography In Correctly Identify Viable Segments On Cardiovascular Magnetic Resonance1368Absolute wall thickening and left ventricular ejection fraction–a unifying theory of myocardial contraction and heart failure?1376Transient St Elevation in Acs Like Myocarditis1379Patients after Fontan with a “total cavopulmonary connection” Fontan modification develop more collateral flow compared to “old-fashioned” Fontan modifications1387A MRI–derived 3D patient specific model for fibrosis quantification in atrial fibrillation1391Scar burden and survival in patients with ischemic cardiomyopathy and poor LV ejection fraction1392Relation of inflammatory markers with myocardial and microvascular injury in patients with reperfused ST- elevation myocardial infarction1406Equivalence of segmented conventional and fast single-shot late gadolinium enhancement (LGE) techniques for1410Cardiac Mri Appearances of Tuberculosis - A Review of Varied Presentations in India1415Atheroma burden, cardiac remodelling and epicardial fat: A comparison between healthy South Asian and European adults using Whole Body Cardiovascular MR1418Symptomatic Ventricular Arrhythmias: Diagnostic Yield of Cardiac Magnetic Resonance1421CMR assessment of aortic stiffness in asymptomatic low risk patients with type 2 diabetes mellitus1436Shock index as a predictor of myocardial damage and clinical outcome in ST-elevation myocardial infarction1451Combined biomarker testing for the prediction of microvascular obstruction after primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction1452A novel oscillometric technique compared with cardiac magnetic resonance for the assessment of aortic pulse wave velocity in ST-segment elevation myocardial infarction1456Aorto-pulmonary collaterals evaluated by CMR is associated to reduced “effective” cardiac index late after Fontan palliation1458Evaluation of pulmonary transit time and Pulmonary Blood Volume with first-pass perfusion CMR imaging in adult with repaired Congenital Heart disease1459Prognostic value of the cardiac magnetic resonance as a predictor of improvement in ventricular function after TakoTsubo syndrome1462Diagnostic performance of ECG detection of left atrial enlargement in patients with arterial hypertension relative to the cardiac magnetic resonance gold-standard: impact of obesity1463Utility of cardiac magnetic resonance imaging for diagnosis of cardiac sarcoidosis and prediction of therapeutic effects in patients with complete heart block and implanted magnetic resonance-conditional pacemaker: A multicenter study1467Cardiac magnetic resonance late gadolinium enhancement in patients with genetic dilated cardiomyopathy14712.Left ventricular hypertrophy in hypertensive patients–comparison of Cardiac Magnetic Resonance and Echocardiographic analysis of morphological and functional LV-parameters1472Is Angiographic Perfusion Score assessed in patients with acute myocardial infarction correlated with Cardiac Magnetic Resonance infarct size and N-terminal pro-brain natriuretic peptide in 6-month follow-up1476Cardiac Magnetic Resonance Patterns of Left Ventricular Diastolic Function In Hypertrophic Cardiomyopathy1477Impact of platelet volume on thrombus burden and tissue reperfusion in patients with STEMI treated with primary angioplasty: MRI study1479Right ventricle systolic function assessment and its prognostic implications in cardiac amyloidosis1484Cardiac MRI - an important tool in the evaluation of multsystemic inflamatory diseases. An Erdheim-Chester Disease case report1485Predictive value of cardiac magnetic resonance for future adverse cardiac events in patients with ST-segment elevation myocardial infarction1486Time-to-treatment but not thrombectomy influence infarct size and microvascular obstruction in patients with acute ST-segment elevation myocardial infarction treated with primary coronary intervention1489Primary PCI versus Early Routine Post Fibrinolysis PCI for ST Elevation Myocardial Infarction1490Evaluation of ventricular function in Fontan patients undergoing feature tracking magnetic resonance strain1491Impacts of atrialized right ventricle and left ventricular displacement

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Key result

Acute isolated left ventricular STEMI was associated with significantly lower mean right ventricular free wall transverse strain compared to controls (12.40% vs 21.70%, p=0.0001).

Why the study?

Does acute isolated left ventricular STEMI impair right ventricular transverse strain and strain rate compared to controls?

Study Design

Type

Observational (n=38)

Structured PICO

Does acute isolated left ventricular STEMI impair right ventricular transverse strain and strain rate compared to controls?

P

Population

38 participants (mean age 59 years, 40% female) with acute isolated left ventricular STEMI, excluding those with right ventricular myocardial infarction.

E

Exposure

Cardiac magnetic resonance (CMR) feature tracking using TomTec 2D Cardiac Performance Analysis software

C

Comparator

Controls

O

Outcome

Mean and segmental longitudinal and transverse strain and strain rate of the RV free wallsurrogate

Main Result

Absolute Event Rate: 12.4% vs 21.7%

p-value: p=0.0001

CMR feature tracking reveals that transverse strain and strain rate of the RV free wall are impaired in patients with acute isolated left ventricular STEMI, even when longitudinal RV systolic function remains normal.

Implication

Acute LV STEMI may impair RV transverse strain despite preserved longitudinal function; leaves open the prognostic role of CMR feature tracking.

Abstract

Background: Impaired right ventricular (RV) systolic function after acute ST-segment elevation myocardial infarction (STEMI) is associated with poor clinical outcomes. CMR feature tracking technique enables quantification of myocardial deformation and becomes promising method. The aim of this study was to evaluate longitudinal and transverse strain and strain rate of RV free wall in patients with acute isolated left ventricular STEMI using CMR feature tracking. Methods: A total of 38 participants (mean age 59 + 10.8 years; 60% male) were recruited into the study and underwent CMR at 1.5 Tesla (Siemens Magnetom Aera). TomTec 2D Cardiac Performance Analysis software was used to analyze mean and segmental longitudinal and transverse strain and strain rate of the RV free wall. Patients with RV myocardial infarction (LGE of RV myocardium) were excluded. Results: RV free wall longitudinal strain and strain rate parameters did not reach statistical significance. Patients with acute STEMI demonstrated lower mean RV free wall transverse strain (12.40 + 8.10% vs 21.70 + 7.32%, p 0.0001) and strain rate (1.08 + 0.33 s-1 vs 1.51 + 0.38 s-1, p 0.001) than controls. We also performed segmental analysis. Transverse strain was significantly impaired in the basal (15.52 + 8.81% vs 24.52 + 11.29%, p 0.03), mid (11.16 + 8.34% vs 18,21 + 7.57%, p 0.02) and apical (10.52 + 11.53% vs 22.37 + 10.33%, p 0.001) segments of RV free wall in patients with STEMI comparing with controls. Transverse strain rate was lower in the basal (0.97 + 0.44 s-1 vs 1.51 + 0.43 s-1, p 0.001) and mid (0.91 + 0.31 s-1 vs 1.36 + 0.41 s-1, p 0.01) segments in STEMI group. There was no difference between groups for apical transverse strain rate of RV free wall. Conclusions: This study demonstrates that transverse strain and strain rate of RV free wall are impaired in patients with acute isolated left ventricular STEMI while longitudinal RV systolic function remains normal.

Discussion

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Cite This Study

Lapinskas et al. (2016) conducted an observational in Acute isolated left ventricular ST-segment elevation myocardial infarction (n=38). Acute isolated left ventricular STEMI vs. Controls was evaluated on Mean right ventricular free wall transverse strain (p=0.0001). Acute isolated left ventricular STEMI was associated with significantly lower mean right ventricular free wall transverse strain compared to controls (12.40% vs 21.70%, p=0.0001).

synapsesocial.com/papers/6a6a5dfe425eb3a8efb37c8a https://doi.org/10.1093/ehjci/jew183

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Study Design

Structured PICO

Main Result

Implication

Abstract

Discussion

Cite This Study

Study Design

Structured PICO

Main Result

Implication

Abstract

Discussion

Cite This Study

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