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January 5, 2017BMC Cardiovascular DisordersOpen Access

Comparison of global myocardial strain assessed by cardiovascular magnetic resonance tagging and feature tracking to infarct size at predicting remodelling following STEMI

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Why the study?

Does global myocardial strain assessed by CMR acutely following STEMI predict adverse LV remodelling independent of infarct size?

Population

65 patients with acute STEMI, mean age 60 ± 11 years

Comparison

Global peak systolic circumferential strain and… vs Infarct size (IS)

Design

Cohort

Follow-up

4 months

Authors

ASAbhishek ShetyeSNSheraz A. NazirNRNaveed Razvi

Discussion

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Overview

Baseline CMR strain does not predict adverse LV remodelling post-STEMI; hypothesis-generating for its incremental value beyond infarct size.

Structured PICO

Does global myocardial strain assessed by CMR acutely following STEMI predict adverse LV remodelling independent of infarct size?

P
Population
65 patients with acute STEMI, mean age 60 ± 11 years
I
Intervention
Global peak systolic circumferential strain (GCS) and global peak systolic longitudinal strain (GLS) measured by cardiovascular magnetic resonance (CMR) tagging and Feature Tracking (FT) at 1-3 days post-reperfusion
C
Comparator
Infarct size (IS)
O
Outcome
Adverse left ventricular (LV) remodelling (composite of end-diastolic volume index [EDVI] ≥20% or end-systolic volume index [ESVI] ≥15% at follow-up compared to baseline) at 4 monthssurrogate

Baseline global strain measured by CMR does not predict adverse LV remodeling following STEMI, whereas infarct size remains a significant predictor.

Cite This Study

Shetye et al. (2017) studied this question.

synapsesocial.com/papers/6a7d4cc0d85f1805a31cd7cahttps://doi.org/10.1186/s12872-016-0461-6
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Left Ventricular Strain Is Associated With Myocardial Recovery Following ST-Elevation Myocardial Infarction, a Prospective Longitudinal CMR Study2022 · 6 citations
  2. 2The role of left ventricular deformation in the assessment of microvascular obstruction and intramyocardial haemorrhage2016 · 24 citations
  3. 3Recovery and prognostic values of myocardial strain in acute anterior and non-anterior wall myocardial infarction2023 · 1 citations
  4. 4Early Cardiac Magnetic Resonance-derived Cardiac Strain as a Predictor of Adverse Events and Ventricular Remodeling in Patients with Reperfused STEMI: A Two-center Cohort Study2023
  5. 5Cardiac Strain as a Predictor of Adverse Events and Ventricular Remodeling: A Cohort Study2020