Key result
LV global longitudinal strain after primary PCI accurately predicts ≥50% reduction in 6-month infarct size.
Why the study?
Infarct size after STEMI determines LV dysfunction and outcomes, and researchers sought to investigate the association between CMR-FT-derived myocardial global strain and myocardial recovery.
Does CMR-FT-derived myocardial global strain predict myocardial recovery in patients with STEMI treated with primary PCI?
Population
14 patients with STEMI treated with primary PCI
Comparison
CMR-FT-derived myocardial global strain parameters
Design
Prospective longitudinal study
Follow-up
6 months
Authors
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LV GLS post-primary PCI may predict STEMI recovery; hypothesis-generating and requires prospective validation before practice change.
Cohort (n=14)
Yes
Does CMR-FT-derived myocardial global strain predict myocardial recovery in patients with STEMI treated with primary PCI?
Effect estimate: AUC 0.97 (95% CI 0.95-0.99)
p-value: p=<0.001
LV global strains measured by CMR-FT early after primary PCI for STEMI strongly correlate with and predict the extent of myocardial recovery at 6 months.
Taha et al. (2022) conducted a cohort in ST-elevation myocardial infarction (STEMI) (n=14). Cardiac magnetic resonance feature tracking (CMR-FT) global strain was evaluated on Prediction of ≥50% decrease in late gadolinium enhancement (LGE) mass by LV global longitudinal strain (AUC 0.97, 95% CI 0.95-0.99, p=<0.001). Left ventricular global longitudinal strain measured after primary percutaneous coronary intervention accurately predicted a 50% or greater reduction in infarct size at 6 months (AUC 0.97).