Key result
GLS improves by ~2% six months post-STEMI while LVEF remains unchanged.
Why the study?
The study sought to assess changes in LV strain and LVEF from acute to chronic STEMI and evaluate strain as a predictor of late gadolinium enhancement.
Does CMR feature tracking strain improve from acute to chronic STEMI, and can it predict late gadolinium enhancement in patients with STEMI?
Population
32 patients with STEMI and 18 controls
Comparison
STEMI patients vs controls, and acute vs chronic post-infarction status
Design
Prospective observational CMR study
Follow-up
six months after infarction (± 1.4 months)
Authors
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GLS recovery post-STEMI may signal viability undetected by stable LVEF; leaves open its role as CMR biomarker pending prospective validation.
Cohort (n=50)
No
Does CMR feature tracking strain improve from acute to chronic STEMI, and can it predict late gadolinium enhancement in patients with STEMI?
Absolute Event Rate: -15.8% vs -13.8%
p-value: p=<0.001
CMR feature tracking strain improves within six months after STEMI and can serve as an imaging biomarker to predict myocardial viability and late gadolinium enhancement.
Erley et al. (2022) conducted a cohort in ST-elevation myocardial infarction (n=50). Cardiac magnetic resonance feature tracking vs. Baseline (8 ± 5 days post-infarction) was evaluated on Left ventricular global longitudinal strain (LV GLS) (p=<0.001). Global longitudinal strain significantly improved from -13.8% at baseline to -15.8% at six months after ST-elevation myocardial infarction, while left ventricular ejection fraction remained unchanged.
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