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March 14, 2023Open Access

Early Cardiac Magnetic Resonance-derived Cardiac Strain as a Predictor of Adverse Events and Ventricular Remodeling in Patients with Reperfused STEMI: A Two-center Cohort Study

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Why the study?

The study investigated the predictive value of CMR-derived strains for post-infarction left ventricular adverse remodeling and clinical events in an East Asian cohort of STEMI patients.

Does early CMR-derived global longitudinal strain predict MACE and left ventricular adverse remodeling in STEMI patients treated with primary PCI?

Population

76 STEMI patients treated with primary PCI at two centers

Comparison

CMR-derived cardiac strain assessed by feature tracking

Design

Two-center prospective cohort study

Follow-up

6-month follow up

Authors

ZZZuoyi ZhouPeking UniversityYLYuan LüGuiyang Medical UniversityZWZhi WangHebei Medical University

Discussion

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Implication

CMR strains may predict post-STEMI LVAR and events in East Asians; hypothesis-generating, needs prospective validation before clinical use.

Structured PICO

Does early CMR-derived global longitudinal strain predict MACE and left ventricular adverse remodeling in STEMI patients treated with primary PCI?

P
Population
76 East Asian patients with STEMI treated with primary PCI (stent implantation), mean age 55.5 ± 10.7 years, 88% male.
I
Intervention
Early cardiac magnetic resonance (CMR) imaging with feature tracking to assess left ventricular (LV) strains (specifically global longitudinal strain, GLS).
O
Outcome
Major adverse cardiac events (MACE) and left ventricular adverse remodeling (LVAR, defined as 15% increase in LV end-diastolic volume) at 6-month follow-up.composite

Early CMR-derived global longitudinal strain is an independent predictor of MACE and adverse left ventricular remodeling in STEMI patients following primary PCI.

Cite This Study

Zhou et al. (2023) studied this question.

synapsesocial.com/papers/6a7983ee1bd2924d66f36d1fhttps://doi.org/10.21203/rs.3.rs-2670313/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The role of left ventricular deformation in the assessment of microvascular obstruction and intramyocardial haemorrhage2016 · 24 citations
  2. 2Comparison of global myocardial strain assessed by cardiovascular magnetic resonance tagging and feature tracking to infarct size at predicting remodelling following STEMI2017 · 27 citations
  3. 3Cardiovascular magnetic resonance myocardial feature tracking detects quantitative wall motion during dobutamine stress2011 · 155 citations
  4. 4Five-Year Outcomes and Prognostic Value of Feature-Tracking Cardiovascular Magnetic Resonance in Patients Receiving Early Prereperfusion Metoprolol in Acute Myocardial Infarction2020 · 22 citations
  5. 5Redefining Adverse and Reverse Left Ventricular Remodeling by Cardiovascular Magnetic Resonance Following ST-Segment–Elevation Myocardial Infarction and Their Implications on Long-Term Prognosis2020 · 46 citations