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To identify factors associated with the risk of developing dementia in patients with diabetes aged 65 years or older.

Risk factors for dementia in patients over 65 with diabetes

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To identify factors associated with the risk of developing dementia in patients with diabetes aged 65 years or older.
Retrospective, longitudinal study using a national cohort of US Veterans with diabetes.
Examined incidence of dementia over 2 years.
Utilized a multivariable Cox regression model to assess risk factors.
Among 377,838 patients, 14,580 (3.85%) were diagnosed with dementia over 2 years.
Age >75 years (HR 2.092 for 75-85 years; HR 3.468 for ≥85 years), race, and Southern residence were significant risk factors.
Use of oral hypoglycemic agents and HMG-CoA reductase inhibitors showed reduced risk (HR 0.940 and HR 0.875, respectively).

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Retrospective study identifies risk and protective factors for dementia in older diabetic patients, suggesting potential interventions.

Parikh et al. (2010) studied this question.

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