Key result
In chronically decentralized canine hearts, 57% of atrial and 62% of ventricular neurons exhibited spontaneous activity correlated with the cardiac cycle.
Intracardiac neurons in chronically decentralized canine hearts generate spontaneous activity that correlates with cardiovascular and respiratory events and respond to local mechanical distortion.
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Decentralized cardiac ganglia retain cycle-related activity in dogs; leaves open independent role in human autonomic regulation.
Ardell et al. (1991) studied Chronically decentralized canine hearts (n=8). Chronic decentralization of the heart was evaluated on Spontaneous activity of atrial and ventricular neurons. In chronically decentralized canine hearts, 57% of atrial and 62% of ventricular neurons exhibited spontaneous activity correlated with the cardiac cycle.
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