Why the study?
Does chronic surgical decentralization alter the intracellular properties and neurotransmission of canine intracardiac neurons in vitro?
Does chronic surgical decentralization alter the intracellular properties and neurotransmission of canine intracardiac neurons in vitro?
Chronic decentralization of intrinsic cardiac neurons leads to changes in membrane properties that may increase excitability while maintaining synaptic neurotransmission.
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May enhance excitability of decentralized canine intracardiac neurons while preserving transmission; leaves open relevance to human autonomic remodeling.
Smith et al. (2001) studied this question.
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