What is the clinical evidence from this study?

Study design: Cohort. Population: History of aborted sudden cardiac death or refractory ventricular tachyarrhythmias (n=231). Intervention: ICD implantation in the prepectoral subfascial position under conscious sedation. Primary outcome: First-year total survival.

What question did this study set out to answer?

This study aims to assess the long-term safety and efficacy of implantable cardioverter-defibrillators (ICDs) implanted using a simplified technique under conscious sedation.

February 18, 1997Circulation

Long-term Follow-up of Cardioverter-Defibrillator Implanted Under Conscious Sedation in Prepectoral Subfascial Position

View Full Paper

Ask AI

Bookmark

Key result

Implantation of ICDs in the prepectoral subfascial position under conscious sedation was successful in all 231 patients, with no operative mortality and a 97% first-year total survival.

Why the study?

Does prepectoral subfascial ICD implantation under conscious sedation provide a safe and effective long-term outcome in patients requiring ICDs?

Population

231 consecutive patients with a history of aborted sudden cardiac death or refractory ventricular…

Design

Cohort

Follow-up

averaging 453 +/- 296 days

Authors

APAntonio PacificoUniversity of L'Aquila KWKevin R. WheelanBaylor Jack and Jane Hamilton Heart and Vascular Hospital NNNadim NasirIraqi University

Discussion

Member takes

Implication

Supports feasibility of conscious sedation for prepectoral subfascial ICDs; leaves open need for randomized comparison to conventional approaches.

Key Points

This study aims to assess the long-term safety and efficacy of implantable cardioverter-defibrillators (ICDs) implanted using a simplified technique under conscious sedation.
Prospective evaluation of 231 consecutive patients with various cardiac conditions.
ICD implantation performed under conscious sedation with midazolam and propofol in electrophysiology laboratories.
Follow-up averaged 453 days to assess long-term outcomes.
Successful implantation in all patients with a first-year survival rate of 97%.
One pocket hematoma, one seroma, and one pneumothorax treated; no major complications noted.
Six leads required repositioning, but no infections or erosions occurred.

Study Design

Type

Cohort (n=231)

Structured PICO

Does prepectoral subfascial ICD implantation under conscious sedation provide a safe and effective long-term outcome in patients requiring ICDs?

Population

231 patients (mean age 63, 13.5% female) receiving ICDs in the prepectoral subfascial position under conscious sedation, followed for an average of 453 days.

Exposure

Insertion of transvenous leads and prepectoral subfascial implantable cardioverter-defibrillator (ICD) implantation under local anesthesia and conscious sedation with intravenous midazolam and propofol.

Outcome

Safety, efficacy, and long-term follow-up of the simplified implantation procedure (including operative complications, mortality, lead repositioning, and pocket erosions/infections).safety

Prepectoral subfascial ICD implantation under conscious sedation is a safe and feasible procedure with low complication rates and excellent long-term survival.

Cite This Study

Pacifico et al. (1997) conducted a cohort in History of aborted sudden cardiac death or refractory ventricular tachyarrhythmias (n=231). ICD implantation in the prepectoral subfascial position under conscious sedation was evaluated on First-year total survival. Implantation of ICDs in the prepectoral subfascial position under conscious sedation was successful in all 231 patients, with no operative mortality and a 97% first-year total survival.

synapsesocial.com/papers/6a6a8cbd01245da06ecb389e https://doi.org/10.1161/01.cir.95.4.946

Topics

HFrEF treatment Cardiac device therapy Heart failure

View Full Paper

Ask AI

Bookmark

Implication

Supports feasibility of conscious sedation for prepectoral subfascial ICDs; leaves open need for randomized comparison to conventional approaches.

Long-term Follow-up of Cardioverter-Defibrillator Implanted Under Conscious Sedation in Prepectoral Subfascial Position

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Topics

Long-term Follow-up of Cardioverter-Defibrillator Implanted Under Conscious Sedation in Prepectoral Subfascial Position

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider