Key result
Among 56 patients, partial IVC interruption (n=30) resulted in a substantially higher recurrence rate of pulmonary embolus and more recurrence-related deaths compared to IVC ligation (n=26).
Why the study?
Does IVC plication compared to IVC ligation improve outcomes in patients with pulmonary embolism failing anticoagulation?
Population
56 patients with pulmonary embolism who failed preoperative anticoagulants
Comparison
Partial interruption of the inferior vena cava vs Inferior vena cava (IVC) ligation
Design
Cohort
Authors
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May favor ligation over plication to reduce recurrent PE; hypothesis-generating and should not yet change practice.
Cohort (n=56)
Does IVC plication compared to IVC ligation improve outcomes in patients with pulmonary embolism failing anticoagulation?
IVC ligation may be superior to IVC plication in preventing recurrent pulmonary emboli and associated mortality in patients failing anticoagulation.
EBERLEIN et al. (1974) conducted a cohort in Pulmonary embolism (n=56). Partial interruption of the inferior vena cava (plication) vs. Inferior vena cava ligation was evaluated on Recurrence of pulmonary embolus. Among 56 patients, partial IVC interruption (n=30) resulted in a substantially higher recurrence rate of pulmonary embolus and more recurrence-related deaths compared to IVC ligation (n=26).
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