Why the study?
Does ligation of the inferior vena cava prevent recurrent pulmonary embolism?
Does ligation of the inferior vena cava prevent recurrent pulmonary embolism?
Contrary to prior belief, inferior vena cava ligation may be associated with a significant rate of recurrent pulmonary embolism.
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May not reliably prevent recurrent PE; hypothesis-generating case series that leaves efficacy open pending controlled studies.
THE rationale for venous ligation in pulmonary embolic disease is based on its assumed ability to prevent subsequent emboli from reaching the lungs. The level of the inferior vena cava is now generally accepted as the site of choice for ligation since anatomically its effectiveness appears assured. Recurrence of pulmonary embolism after this procedure is believed to be rare.1 2 3 This paper reports the findings in 9 patients with apparent pulmonary emboli that followed ligation suggesting that, contrary to current opinion, there is a significant recurrence rate. These patients, who were encountered over a period of two and a half years . . .
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Gurewich et al. (1966) studied this question.
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