Hodgkin's disease presenting with hypoadrenalism.

August 21, 1976BMJOpen Access

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Key Points

To compare the effects of practolol and atenolol on cardiac output and blood gases in patients with Hodgkin's disease presenting with hypoadrenalism.
Compared cardiac output and blood gases in 11 patients using practolol and atenolol during rest and exercise.
Measured outcomes included cardiac output, Paco2, and Pao2 at various intervals (5 min, 45 min, and after isoprenaline administration).
Average cardiac output at rest was 6.66 (practolol) vs. 6.40 (atenolol) without significant difference.
During exercise, practolol achieved a higher cardiac output (12.67 vs. 11.02 for atenolol).
Blood gas measurements (Paco2 and Pao2) varied with both drugs, indicating different physiological responses.

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Compares the effects of practolol and atenolol on cardiac output in hypoadrenalism patients, suggesting potential treatment differences.

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Feinmann et al. (1976) studied this question.

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