Key result
Preoperative serum creatinine ≥0.9 mg/dl was independently associated with significantly higher rates of recurrent hypertension after adrenalectomy for primary aldosteronism.
Why the study?
Does preoperative serum creatinine predict recurrent hypertension in patients with primary aldosteronism after adrenalectomy?
Population
46 patients with primary aldosteronism (PA) who had undergone adrenalectomy between 1976 and 1998
Design
Cohort
Follow-up
average 12.2 years
Authors
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May warrant closer post-adrenalectomy surveillance in higher-creatinine patients; leaves open whether thresholds should guide surgical decisions.
Cohort (n=46)
Does preoperative serum creatinine predict recurrent hypertension in patients with primary aldosteronism after adrenalectomy?
Preoperative subclinical renal damage, indicated by serum creatinine ≥0.9 mg/dl, is an independent predictor of recurrent hypertension after adrenalectomy for primary aldosteronism.
Fukudome et al. (2002) conducted a cohort in Primary aldosteronism (n=46). Preoperative serum creatinine ≥0.9 mg/dl vs. Preoperative serum creatinine <0.9 mg/dl was evaluated on Recurrent hypertension. Preoperative serum creatinine ≥0.9 mg/dl was independently associated with significantly higher rates of recurrent hypertension after adrenalectomy for primary aldosteronism.
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