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August 1, 1996Annals of SurgeryOpen Access

Primary Aldosteronism

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Why the study?

Does adrenal surgery improve hypertension and hypokalemia in patients with primary hyperaldosteronism?

Population

46 patients who had adrenal surgery for primary hyperaldosteronism from 1983 to 1994

Design

Cohort

Follow-up

mean 51 months

Authors

CLChung Yau LoUniversity of Hong KongPTPo Chor TamQueen Mary HospitalAKAnnie W. C. KungUniversity of Hong Kong

Discussion

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Overview

Adrenalectomy may allow most APA patients to stop antihypertensives long-term; leaves open need for RCTs to guide selection and confirm durability.

Structured PICO

Does adrenal surgery improve hypertension and hypokalemia in patients with primary hyperaldosteronism?

P
Population
46 patients who had adrenal surgery for primary hyperaldosteronism from 1983 to 1994
I
Intervention
Adrenal surgery
O
Outcome
Postoperative persistent hypertension

Adrenal surgery for aldosterone-producing adenomas is safe and cures hypertension in the majority of patients, though some may have persistent mild hypertension.

Cite This Study

Lo et al. (1996) studied this question.

synapsesocial.com/papers/6a7245be3ce530166bc34a04https://doi.org/10.1097/00000658-199608000-00003

Topics

Hypertension management
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Surgical Treatment of Primary Hyperaldosteronism1994 · 43 citations
  2. 2Control of Plasma Aldosterone in Primary Aldosteronism: Distinction Between Adenoma and Hyperplasia1973 · 192 citations