Why the study?
Does adrenalectomy improve blood pressure in patients with primary aldosteronism with or without unilateral adenoma?
Population
168 patients with primary aldosteronism undergoing surgery
Comparison
Adrenalectomy vs Patients with unilateral adenoma vs. patients…
Design
Cohort
Authors
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Adrenalectomy was associated with hypertension improvement in most primary aldosteronism patients regardless of CT laterality; leaves open whether AVS should guide surgery in non-lateralized cases.
Does adrenalectomy improve blood pressure in patients with primary aldosteronism with or without unilateral adenoma?
Adrenalectomy improves blood pressure control in primary aldosteronism regardless of whether lateralization is detected by CT (unilateral adenoma) or adrenal venous sampling, with higher baseline urinary aldosterone and lower serum potassium predicting better outcomes.
Letavernier et al. (2008) studied this question.