Key result
Higher baseline brachial-ankle pulse wave velocity independently predicted new onset of hypertension, with a hazard ratio of 3.49 (95% CI 2.66-4.57) for the highest versus lowest tertile.
Why the study?
Does baseline brachial-ankle pulse wave velocity predict new onset of hypertension and longitudinal increases in blood pressure in individuals without hypertension?
Population
2,496 participants (aged 27-84 years) without hypertension attending a yearly hospital health check-up
Comparison
Baseline brachial-ankle pulse wave velocity… vs Lower tertiles of baPWV
Design
Cohort
Follow-up
median 733 days (up to 4 years)
Authors
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Does not support routine baPWV use; hypothesis-generating for prevention trials in normotensives.
Cohort (n=2,496)
No
Does baseline brachial-ankle pulse wave velocity predict new onset of hypertension and longitudinal increases in blood pressure in individuals without hypertension?
Hazard Ratio: 3.49 (95% CI 2.66–4.57)
p-value: p=<0.001
Baseline brachial-ankle pulse wave velocity is an independent predictor of longitudinal blood pressure increases and incident hypertension in normotensive individuals.
Takase et al. (2011) conducted a cohort in Normal blood pressure (without hypertension) (n=2,496). Brachial-ankle pulse wave velocity (baPWV) vs. First tertile of baseline baPWV was evaluated on Development of hypertension (HR 3.49, 95% CI 2.66-4.57, p=<0.001). Higher baseline brachial-ankle pulse wave velocity independently predicted new onset of hypertension, with a hazard ratio of 3.49 (95% CI 2.66-4.57) for the highest versus lowest tertile.
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